Please note that this site is currently under construction - please check back in a few days for more information. The Center for Bioinformatics and Computational Biology at the University of Maryland has compiled a collection of sequence data from several bacterial genomes for benchmarking sequence assembly software. A collaboration of four research institutes. Free for research and educational use.Īn open source software package for aligning whole genomes.Ī Modular, Open Source whole genome assembler.

Se-Al - An older sequence alignment editor for Mac OS X. Several sequence manipulation and analysis options and links to external analysis programs facilitate a working environment which allows you to. An intuitive multiple document interface with convenient features makes alignment and manipulation of sequences relatively easy on your desktop computer. Not the most user-friendly package, steep learning curve. BioEdit is a biological sequence alignment editor. Staden Package - a powerful open source sequence assembly and editing package for UNIX, Linux, Windows, and Mac OS X. Free for research and educational use.Ī sequence assembly program for whole genome assemblies from short ('next generation') sequencing reads from MIT's Broad Institute. BioEdit - a very popular free sequence alignment editor for Windows. Assembles Sanger sequencing data and Roche 454 data.Ī whole genome assembler for Sanger sequencing reads developed at the Broad Institute. The program that was used to assemble the first human genome, released as open source in 2004. Phrap pioneered a number of important idea, including the automatic use of entire sequences without trimming and accurate consensus sequences based on sequence qualities and confirmation by other reads. The sequence assembly program Phrap was developed to assemble shotgun cosmid and BAC sequencing projects in the Human Genome Project. Part of the Staden package of DNA sequence analysis tools. Open source sequence assembler for Sanger sequencing. Free and Open Source Sequence Assembly Programs Gap4 / Gap5 An overview of different problems and approaches is available on Wikipedia. Sequence assembly refers to the process of merging DNA fragments into larger 'contigs' for subsequent analysis. This site is dedicated to software for DNA sequence assembly and alignment.

Bioedit software online